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ZYMOX hot spot spray for dogs and cats promotes relief from itching, allergies and hot spots. ZYMOX Topical Spray is a Hydrocortisone-free formula for sensitive, pregnant or lactating pets. It is also available with 1% Hydrocortisone to calm irritated skin and aloe vera to soothe redness and inflammation.
Our anti-itch spray for dogs and cats also soothes skin wounds and infections. The no-sting formula with the ZYMOX LP3 Enzyme System aids recovery from skin infections caused by germs, fungi and yeast.
ZYMOX Spray is Ideal for use on:
- Skin bumps and pustules
- Red, irritated or inflamed skin
- Itchy skin
- Red, discolored paws, irritated by licking
- Red, bald patches, often irritated by licking
- Wounds and cuts
- Infected skin
- Hot spots
ZYMOX Spray is simple to use - spray onto the affected area once or twice a day, for up to seven days.
Because ZYMOX hot spot spray for dogs and cats only contains safe, gentle and non-toxic ingredients, it’s safe if your inquisitive pet licks the application site.
Recurrent skin infections, hot spots and irritation can lead to a distressed pet and repeat visits to your veterinarian. They can also mean repeat courses of medication, which can lead to problems with resistant bugs that don’t respond to conventional medicinal treatment.
The ZYMOX LP3 Enzyme System is effective on a broad spectrum of germs, fungi and yeast that cause skin problems.
Enzymes are naturally-occurring proteins, and the LP3 Enzyme System from ZYMOX helps destroy microorganisms without attacking healthy cells or irritating the skin. Enzymes don’t develop a resistance to microbes and will continue to work for your pet when they need them.
There’s no need to pre-clean sore areas first. Simply spray without cleaning. The enzymes react with organic matter within the skin helping to manage infections and hot spots.
ZYMOX Topical Spray includes 1% Hydrocortisone for relief from itching and inflammation.
ZYMOX Topical Spray is also available without Hydrocortisone for sensitive animals, rodents, exotics, pets sensitive to Hydrocortisone and pets that are pregnant or lactating.
ZYMOX Topical Spray is an all-in-one solution for infections caused by germs, fungi and yeast.
Enzymes do not develop a resistance to microbes, so this spray will continue to work for your pet.
The LP3 Enzyme System reacts with biological materials in the skin to form its powerful soothing properties.
Simple, effective relief.
Apply once or twice a day by spraying the entire affected area.
There’s no need to cause fear or upset in your pet, as there’s no painful pre-cleaning necessary.
Pre-cleaning and cleaning during use disrupts the biological system and will negatively affect results.
sidney r humes
Reviewed in the United States on March 25, 2025
Awesome product, some of it was delivered spilled inside of package.
Karren Lore
Reviewed in the United States on September 30, 2024
Spray on an area where she's scratching or biting. She stops scratching or biting that place for several hours. Just have to keep on top of it until the spot heals.
jacqueline bioret
Reviewed in the United States on May 27, 2024
Easy to spray the infected spots , improvement in 3 to 5 days, I recommended.
Mr. A. Patterson
Reviewed in the United Kingdom on February 19, 2024
Just what I wanted, perfect
Customer
Reviewed in the United States on November 28, 2024
dogs lick their paws..they do..don't believe the social media ads that it is a food issue..but it might be..and it might be yeast..yeast will get deep inbetween pads..and licking keeps it wet and growing..this wipes out yeast but it takes a long time..yeast is stubborn..and comes back..use periodically..get it down between the pads. helps to trim if very furry there..to help dry out.
Tina Fenske
Reviewed in the United States on August 21, 2023
Used for hot spot on our dogs inner leg. Cleared it up completely within 2 weeks. Our dog also gets inflamated paw pads from excessive licking. This calms the raw spot and also prevents further licking as it probably doesn't taste good
Customer
Reviewed in the United Kingdom on March 30, 2023
Instantly stops my frenchie from going at his paws really pleased with product, although very expensive it’s better than vets bills !!
None
Reviewed in the United Kingdom on January 3, 2023
Good price for this product.My dog has had prescribed stay for most of his life due to allergies etc. this worked better the the vet prescribed spray.I would recommend this product.
Kawa
Reviewed in the United States on April 23, 2023
Works well for pet skin allergies.
Raymond Harris
Reviewed in the United Kingdom on February 4, 2022
tried but seen no difference
Anna-Marie Boatman
Reviewed in the United Kingdom on May 30, 2020
Handy little bottle to have around.
Andrea G. Kittell
Reviewed in the United States on September 20, 2016
9-20-16 BEWARE OF LEAKING OF THE SPRAY OIL---I DON'T KNOW WHY WITH A CAP, AND SEALED PLASTIC, BUT PLASTIC COVERED IN OIL. HAD TO CLEAN BOTTLE. 2oz is so litte, hard to know if just small bit. My point is, whether 13$ price justifies some leaking, it's not about price, simply, it's good business to fix the problem, many places to choice to order.Otherwise, fix that, if it works same quality as the ear solution has, it's a BLESSING. German Shepherds, both very big, hike often, get into every area from plants to water to digging down in their searches, so, trying the spray 1st time(WILL update) because: first year having a heat rash issue from abdomen where thighs start to end of back of the leg. NO way it can consistently heal by drying out in the season of hiking and tons of allergens, fungi, staph, or certain water of streams, etc. I hope as effective as EAR SOLUTION. HELPED 100%
Experienced Reviewer
Reviewed in the United States on October 10, 2014
This is the third Zymox product I have tried. I tried the drops for the ears first and they worked beautifully. Then a few months later my puppy developed a rash on the ear margins. She was getting crusty scabs and while it did not bother her much, it bothered me and she was losing her fur!I first tried the Zymox cream and it worked but it seemed to heavy and would leave her ear feeling and looking matted down and greasy.I decided to try the Zymox spray instead. My westie puppy did not like the sound of the spray so I just open the cap and apply some with my finger to saturate her ear margins inside and out. I am generous with it but not pouring it on. When it dries it might be slightly sticky but not nearly as bad as with the cream.I am not using any of the products with hydrocortisone at this time. I am also washing the area twice a day with a mild vinegar and water solution before I apply the zymox.I love Zymox without hydrocortisone for my dog and I feel it is safe to use compared to other options. I would recommend this for a dog or cat with any skin issue. It will address, yeast, bacteria and probably anything except a systemic cause.
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